Measurement – First Step in Laboratory Work
Understanding accuracy, calibration, and the science behind laboratory instruments.
Why Measurement Matters
Measurement is the foundation of laboratory science. From mass and volume to pH and color,
every reliable result begins with a well-calibrated instrument. Among all quantities,
mass was one of the first that humans attempted to measure and standardize — shaping trade, science, and trust across civilizations.
To explore the evolution of mass measurement, visit our article:
From Ancient Balances to Analytical Precision
Understanding Accuracy vs. Precision
- Accuracy refers to how close a measurement is to the true value.
Example: hitting the bullseye on a target. - Precision describes how consistent repeated measurements are.
Example: clustering shots tightly together, even if off-center.
Calibration: The Science of Precision
Regular calibration ensures that instruments remain accurate and precise over time.
Environmental factors, wear, and drift can affect readings — calibration corrects these deviations.
- ✅ Ensures true values
- ✅ Improves consistency
- ✅ Maintains compliance (ISO 17025, CE)
Common Calibration Methods
Instrument Type | Calibration Method |
---|---|
Balances & Scales | Certified weights (OIML Class E1–F2) |
Spectrophotometers | Standard light sources |
pH Meters | Buffer solutions (pH 4.00, 7.00, 10.00) |
Colorimeters | Reference tiles or solution standards |
How Often Should Calibration Be Done?
- Daily or Before Use: pH meters, balances
- Monthly to Quarterly: Spectrophotometers
- Annually: Regulatory instruments or as per manufacturer
Related Resources
Frequently Asked Questions (FAQ)
How often should balances be calibrated?Critical balances should be calibrated daily or before each use. Less sensitive instruments may follow monthly or quarterly schedules.
What’s the difference between mass and weight?Mass is the amount of matter in an object; weight is the force of gravity acting on that mass. Mass remains constant, weight varies by location.
What is OIML and why does it matter?OIML is the International Organization of Legal Metrology. It defines global standards for accuracy classes and calibration procedures for measuring instruments.